1. Bio Palette

https://www.biopalette.co.jp/

· Year Founded: 2017

· Total Raised to Date: $15.4M

· Overview:

Bio Palette is a company that uses bacteria bred by genome editing to modify and control the microbiome, based on its proprietary base editing (Genome Editing Without Cutting®).

2. ThinkCyte

https://thinkcyte.com/

· Year Founded: 2016

· Total Raised to Date: $49.5M

· Overview:

ThinkCyte is a developer and provider of next-generation, ultra-fast, highly accurate, image-recognition-based, real-time cell separation systems that utilize AI.

3. CellAxia

https://www.cellaxia.co.jp/

· Year Founded: 2017

· Total Raised to Date: $14.0M

· Overview:

CellAxia is a company developing E-MNC (CA-702), a novel cell therapy effective against refractory autoimmune diseases.

4. Metcela

https://www.metcela.com

· Year Founded: 2019

· Total Raised to Date: $20.9M

· Overview:

Metcela is the developer of MTC001, a combination product that combines autologous cardiac fibroblasts (VCAM1 positive cardiac fibroblasts) with a novel catheter for administration.

5. Integriculture

https://integriculture.jp/

· Year Founded: 2015

· Total Raised to Date: $11.1M

· Overview:

Integriculture is a company that researches and develops useful ingredients, cosmetics, foods, and cell culture meat using the general-purpose large-scale cell culture system "CulNet System".

6. TBM

https://tb-m.com/

· Year Founded: 2011

· Total Raised to Date: $327.8M

· Overview:

TBM is a company that develops, manufactures, and sells LIMEX, a new material made primarily from limestone that can replace paper with virtually no water or wood pulp, and can replace plastic with less petroleum-derived materials.

7. LUCA Science

https://luca-science.com/

· Year Founded: 2018

· Total Raised to Date: $10.3M

· Overview:

LUCA Science is a company that researches and develops therapies for mitochondrial diseases and related disorders to improve and stabilize the condition by controlling mitochondrial activity.

8. Kyulux

https://www.kyulux.com

· Year Founded: 2015

· Total Raised to Date: $191.3M

· Overview:

Kyulux is a company that develops and markets next-generation materials for OLED displays and lighting.

9. Periotherapia

https://periotherapia.co.jp/

· Year Founded: 2017

· Total Raised to Date: $7.7M

· Overview:

Periotherapia is a company that develops drugs for the treatment of refractory (triple negative) breast cancer, which does not respond well to existing anticancer drugs.

10. Tsubame BHB

https://tsubame-bhb.co.jp/

· Year Founded: 2017

· Total Raised to Date: $22.6M

· Overview:

Tsubame BHB is a company engaged in the practical application of on-site ammonia production in small-scale plants using electrolide catalysts.

11. tiem factory

https://www.tiem.jp/

· Year Founded: 2012

· Total Raised to Date: $14.4M

· Overview:

tiem factory is a company that researches, develops, and sells sufa, a general-purpose transparent heat insulator aerogel that is the lightest and has the highest heat insulation performance of any solid on earth.

12. U-MAP

https://umap-corp.com

· Year Founded: 2016

· Total Raised to Date: $3.4M

· Overview:

U-MAP is a company that researches and develops highly functional and conductive materials using Thermalnite, a fibrous aluminum nitride single crystal that is a filler material with both high thermal conductivity and insulation properties.

13. ORTHOREBIRTH

http://orthorebirth.com

· Year Founded: 2011

· Total Raised to Date: $22.2M

· Overview:

ORTHOREBIRTH is a company that provides ReBOSSIS, a cotton-shaped artificial bone filler with features of bone formation and good handling, and ReBOSSIS QDS, a combination of ReBOSSIS and syringe.